FTA:
“Is it the same in the mouse or not?”
The group decided to look, expecting to find some similarities. But when the data were analyzed, there were none at all.
“We were kind of blown away,” Dr. Davis said.
The drug failures became clear. For example, often in mice, a gene would
be used, while in humans, the comparable gene would be suppressed. A
drug that worked in mice by disabling that gene could make the response
even more deadly in humans.
...
Here is a link to the original publication in PNAS
and comments on WUWT.
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